HOT MELT FRAGMENTATION*
(B2C - F)

Conventional hot melt extrusion requires significant downstream processing such as size reduction after the formation of melt and is not amenable for applications involving low melting excipients such as lipids. Typical size reduction processes involve generation of plastic energy which needs to be dissipated efficiently for optimum milling to take place. STEERLife’s proprietary hot melt fragmentation technology provides uniform shear fields  which enables size reduction  of materials with lower melting point or glass transition to take place within the equipment itself, a process which we have termed as “fragmentation:. The technology results in much more uniform size and a narrower distribution in comparison with the Erdmenger geometry.

*Patented

PROCESSES DEVELOPED USING STEERLife’s PROPRIETARY TECHNOLOGIES HAVE THE FOLLOWING FEATURES:

Seamless continuous processes  eliminating hot spots and dead zones (minimal stagnation)

Quality by Design
(well established risk and product quality)

Self cleaning (self-wiping) systems, used as enablers, ensuring no residues of earlier runs

Greater control
over work

Significantly lower
manufacturing footprint

Economical development

Ease of scalability
(both linear and non-linear)

Traceability due to material flowing in stratified continuous stream through the equipment

Negligible waste
resulting in greener processes

Versatility to meet differentiated needs including the ability to handle sensitive materials